The NFL exhibition period has concluded, and now the complete concentration shifts to the Week 1 NFL program, which is now just a few days from commencing. It’s another compelling initial schedule that starts with Cowboys vs. Eagles in the 2025 NFL Kickoff Game on Thursday, followed by Chiefs vs. Chargers in Brazil on Friday. Thirteen contests are on the Sunday lineup, with Vikings vs. Bears finishing it up on Monday. NFL gamblers are often aiming for point spreads, over/unders and straight-up NFL predictions. Some noteworthy Week 1 NFL numbers include the Eagles at -7.5 against the Cowboys, which has changed a half point since the Micah Parsons trade, and the Vikings at -1.5 against Chicago. The Bills, in the meantime, are -1.5 against the Ravens in a Sunday Night Football matchup between AFC contenders.
A collection of precise Week 1 NFL score forecasts can provide you with the resources needed to create a variety of selections for each contest, as well as a guide for some NFL props you might consider. Successfully predicting an exact NFL score could also lead to a significant payout. Before making any Week 1 NFL choices, be sure to check out the precise NFL score predictions from SportsLine expert Eric Cohen.
A SportsLine expert and presenter, Cohen is assessing the entire Week 1 NFL program and provides score predictions and reasoning for each game. He concluded the 2024-25 season with a 190-95 record on outright NFL predictions (69%) and generated revenue for gamblers. Anyone who heeded Cohen’s NFL forecasts has been successful at their preferred sports wagering sites and wagering apps.
You can only view Cohen’s Week 1 NFL exact score forecasts at SportsLine.
Top Week 1 NFL picks
After analyzing all 16 games from the NFL’s Week 1, Cohen anticipates the Bills (-1, 51.5) to narrowly secure a victory in a rematch of their AFC Divisional Playoff Game triumph over the Ravens in a 26-23 final. “In my estimation, these are the two premier teams in the NFL and we’ll witness this matchup again on Sunday, January 25th, 2026 in the AFC Championship Game.”
“I am projecting Buffalo to achieve a 15-2 record this season but Baltimore to win the Super Bowl. If I were to rank home field advantage, the enthusiastic Bills supporters would easily be in the top-5, if not No. 1 overall. That’s the deciding factor in a game that should mirror last year’s playoff contest narrowly won by Buffalo.” With that score projection, Cohen favors the Bills on the straight-up bet (-111), to cover the spread and for the Over to be successful in this matchup. View his other Week 1 football score forecasts at SportsLine.
How to make Week 1 NFL score predictions
Furthermore, Cohen is predicting one game to surpass 60 total points this week, making the Over an essential wager. Accurately forecasting this outcome is crucial for making profitable Week 1 NFL selections. You can only see it at SportsLine.
Who emerges victorious in every Week 1 NFL game, and which games present a compelling case for betting the over? Visit SportsLine now to access Eric Cohen’s NFL Week 1 score forecasts, all from the NFL expert who correctly predicted nearly 70% of his NFL outright selections last season, and discover the answers.
