March Madness 2026 Bracket: Fade Top Seeds for Upset Picks to Boost Your Odds

Despite recent shifts in the collegiate basketball environment that have generally favored top-ranked teams, this does not imply that higher seeds are guaranteed victors over the course of the next three weeks. We must consistently consider prominent institutions that might be susceptible to early exits, and today, we will examine four distinguished programs (including a 1, 2, 3, and 4 seed) that fit this description.

Disclaimer: Statistical data for all teams is sourced from the essential KenPom.com. 

University of Florida, First Seed (South Region)

While a top seed inherently possesses more strengths than weaknesses, it’s reasonable to recognize that the Florida Gators stand somewhat apart from the other three premier seeds. Duke is presently favored to win the title (with Bet MGM listing them at +300), followed closely by Michigan (+350) and Arizona (+400). Florida lags slightly behind at +650. Consequently, any conversation regarding the most susceptible No. 1 seed should commence with Florida.

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The Gators’ formidable frontcourt, which ranked as the nation’s second-best offensive rebounding unit, offers a credible route to consecutive titles. However, questions remain about the proficiency of their backcourt. Florida’s turnover percentage places them 161st, and their three-point shooting conversion rate stands at a mere 30.8%, a surprisingly poor figure for such an esteemed institution.

The University of Florida might also face difficulties due to their regional placement. The second round of the South Regional is scheduled for the Toyota Center in Houston. Coincidentally, the second seed in the South is the Houston Cougars. Supporters of the Gators will likely be subtly hoping for Houston’s early elimination from the tournament, aiming to avert this unfavorable matchup. Houston is not just an ordinary team benefiting from local advantage; they are a genuine championship contender, holding the 5th spot in KenPom’s efficiency metrics.

University of Connecticut, Second Seed (Eastern Region)

Initially, it seems peculiar to dismiss the Huskies, given their two national titles within the past ten years. The athletic program experienced a downturn following the tenure of Kevin Ollie, but Dan Hurley has successfully revitalized it. The Huskies possess a seasoned roster, characterized by stability and consistent player development. While Hurley can be an emotionally charged coach, he also demonstrates exceptional strategic prowess during games. No opponent will underestimate this squad.

However, there’s an argument that UConn received an overly generous No. 2 seeding. The Huskies suffered four losses in their final 11 contests within a Big East conference that underperformed this season, and St. John’s decisively defeated them by 20 points in the Big East Tournament championship. Connecticut struggles with their turnover rate, placing 189th, and rarely earns trips to the foul line, ranking 311th in free throw attempts relative to field goal attempts. Their 11th position in KenPom’s efficiency rankings is respectable, but possibly not indicative of a team deserving of a second seed.

The freshman guard, Braylon Mullins, might prove to be the pivotal player for the Huskies. A strong performance in the tournament could elevate his NBA draft stock to a top 10-13 selection if he chooses to declare. Conversely, a weak showing might compel him to remain in college, though Name, Image, and Likeness (NIL) opportunities would still make that a tempting prospect. Mullins has had difficulty with his shooting over the past three weeks, hitting less than 40% from the field and only 23.4% from beyond the arc. He managed merely five points in the defeat against St. John’s, converting only 2 of his 9 shot attempts.

The Eastern Regional bracket is fraught with potential pitfalls. UCLA possesses the capability to defeat UConn in the second round. Michigan State stands as a formidable third seed. Furthermore, the upper portion of the bracket includes powerhouses such as Duke, Kansas, and St. John’s. While it’s typically challenging to bet against a team coached by Hurley, I am inclined to do so this tournament season.

Gonzaga University, Third Seed (Western Region)

Under Mark Few’s leadership, the Bulldogs have become a nationally recognized basketball powerhouse, consistently qualifying for the tournament since his appointment in the 1999-00 season. This current iteration of the team is well-rounded, showcasing strong offensive capabilities and an exceptionally stifling defense. The Zags relentlessly pressure adversaries into committing turnovers, compel them into poor shot selections, and effectively clear the rebounds after missed attempts. Their play embodies a relentless, full-game intensity.

However, Gonzaga’s offensive performance has declined following the injury to forward Braden Huff in January. Huff has been declared unavailable for the initial two rounds and his return beyond that point is uncertain. In light of this development, it’s not astonishing that Gonzaga’s odds to win the championship are listed at +5500, which are considerably longer than one would anticipate for a well-established, formidable program. The Bulldogs might navigate through the opening week, but I perceive limited potential for them to advance further.

University of Kansas, Fourth Seed (Eastern Region)

Over the past two seasons, the Kansas basketball team has typically performed more strongly during the early part of the academic year compared to the later months. Last season, the Jayhawks commenced as the top-ranked team in national polls but finished the year unranked. This season, the squad began at a credible No. 19 but currently sits outside the top 25. While securing a No. 4 seed is not a discredit, this placement might be a bit optimistic. The Jayhawks hold the 21st position in KenPom’s efficiency standings, making them the lowest-ranked among the fourth seeds.

Attention is focused on the star freshman, Darryn Peterson, whose season has been unusual. He has been absent for 11 complete games and parts of several others, making it difficult for the team to develop cohesion. The key players have simply not spent sufficient time playing together.

The Kansas team concluded its season with a 4-5 losing streak, marked by several decisive defeats. Houston overwhelmed the Jayhawks by 22 points in the Big 12 Tournament. Arizona dominated them with a 23-point victory. Iowa State secured an 18-point win against Kansas. It would not be astonishing if Cal Baptist caused an upset against the Jayhawks in the first round, and I would lean towards St. John’s defeating Kansas in the second round, should that pairing occur.