The roster of pitchers slated for two starts, which appeared quite limited just a couple of days prior, experienced an enhancement over the weekend as the Cardinals, Athletics, and Mets executed pitching staff adjustments that presented fresh alternatives for fantasy managers. Overall, this compilation now represents a moderately strong collection that should satisfy the requirements of those who act swiftly to secure the most advantageous selections.
Regarding offensive players, the Athletics are, by a significant margin, the prime destination for streaming options.
Two-Start Pitchers (listed in order of preference)
Dustin May, Cardinals, 44% (vs. SD, @ KC): May unequivocally emerges as the standout performer among this selection. After a pair of disastrous outings to commence the season, he has delivered outstanding results, achieving a 2.89 earned run average and a 1.09 walks plus hits per inning pitched over his most recent eleven appearances. His impressive performance is thoroughly merited, with the right-handed pitcher accumulating a 59:17 strikeout-to-walk ratio and yielding only three home runs during this eleven-start duration. Facing clubs ranked 30th and 24th in offensive production, May presents a significant transformative asset across all head-to-head league structures.
J.T. Ginn, Athletics, 48% (vs. PIT, vs. LAA): Despite a setback in his latest outing (5.2 innings pitched, 5 earned runs), Ginn has generally performed strongly over twelve starts, maintaining a 2.94 ERA and 1.15 WHIP. The right-arm hurler, while not overpowering (65:30 strikeout-to-walk ratio), consistently induces ground balls, which helps limit home runs. This attribute is particularly crucial at his home stadium, which favors hitters, and where he is scheduled for both appearances this week. Against two lineups known for high strikeout rates, Ginn has the potential to be quite effective and represents one of the limited appealing choices for the current week.
Grant Holmes, Braves, 26% (vs. SF, vs. MIL): As a middling pitcher facing moderately challenging opponents, Holmes holds some attraction in 12-team fantasy baseball leagues. However, it’s important to observe that the right-arm hurler’s recent form has been less than optimal, having failed to complete five innings in two of his last three starts. His potential is limited, primarily due to a pedestrian 8.0 strikeout-per-nine-innings rate, and he has surrendered six home runs across his previous four appearances. Holmes will likely appreciate pitching both games at his home venue, given his career 3.18 ERA at Truist Park compared to a 4.74 ERA when pitching away.
Ryne Nelson, Diamondbacks, 51% (vs. LAA, vs. MIN): Nelson has proven to be among the most erratic starting pitchers in the league, resulting in a 5.19 earned run average. While he has conceded two or fewer earned runs in half of his fourteen starts, he has also endured three games where he gave up six or more earned runs. His most recent poor performance saw the Marlins tally seven runs against him. Nelson’s susceptibility to the long ball, having allowed 17 home runs (fourth-highest in baseball), is the primary cause of his unpredictable nature. With moderate opposition this week, he represents the quintessential high-risk, high-reward choice.
Walbert Ureña, Angels, 41% (@ ARI, @ ATH): Ureña’s 2.44 ERA seems deceptively low, considering he has issued at least three walks in seven of his ten starts. His 4.02 FIP (Fielder Independent Pitching) and 1.36 WHIP (Walks Plus Hits Per Inning Pitched) more accurately reflect a pitcher who is, at best, a league-average performer. Ureña faces manageable opponents, with the Diamondbacks having difficulty against right-handed pitching, and his tendency to induce ground balls might enable him to navigate his game against the Athletics at Sutter Health Park. Individuals participating in points-based fantasy leagues might find him a viable selection.
Jack Perkins, Athletics, 3% (vs. PIT, vs. LAA): Perkins possesses an appealing array of talents but has struggled to find a consistent role. He served briefly as the team’s late-inning reliever in April and is currently being evaluated as a starting pitcher. While his 6.25 ERA might deter most fantasy managers, his 3.68 FIP and 10.8 strikeouts per nine innings suggest untapped potential. Perkins has yielded eight earned runs across eight innings since transitioning back to the rotation, which is sufficient cause to bypass him in category-based leagues. However, participants in points leagues should consider the right-hander, as his impressive ability to generate swings and misses aligns favorably against the two clubs that top the major leagues in strikeouts.
Jared Jones, Pirates, 42% (@ ATH, @ COL): Over an extended period, Jones could emerge as the most captivating pitcher featured here. Nevertheless, he has not been in peak form over his three appearances since being absent for the entirety of 2025, completing the fifth inning in only one of those starts. Under typical circumstances with favorable opponents, I would advocate for taking a gamble on Jones given his considerable abilities. Yet, with scheduled games at two of baseball’s most challenging ballparks—particularly against an Athletics squad that leads Major League Baseball in home OPS—Jones presents an excessive risk this week.
Brandon Young, Orioles, 19% (@ SEA, @ LAD): Primarily as a result of a 53-point enhancement in his Batting Average on Balls In Play (BABIP), Young has experienced increased effectiveness in his sophomore season. The right-arm pitcher has been particularly impressive recently, achieving a quality start and extending into the seventh inning in each of his last four outings. If he were facing less formidable opponents, Young would represent an intriguing speculative choice in a fantasy scoring period with limited strong two-start options. Regrettably, the Dodgers and Mariners are ranked first and eighth, respectively, in On-Base Plus Slugging (OPS) against right-handed pitchers. He is excessively hazardous in category leagues, and his deficient strikeout capabilities restrict his potential in points-based formats.
One-Start Streamers
Presented sequentially, these are the top single-start streaming pitchers for the current week, including their scheduled start day and their Yahoo fantasy roster percentage in parentheses.
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Gage Jump vs. LAA (Thursday, 31%)
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Randy Vásquez @ TEX (Friday, 35%)
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Tatsyui Imai vs. CWS (Friday, 36%)
Favorable Monday-Thursday hitting matchups
Athletics vs. Pirates, Angels: Despite encountering a competent group of four starting pitchers, the batters for the Athletics have an opportunity to capitalize on the sheer number of games—four contests played at their offensive-friendly home stadium. Furthermore, with every scheduled starter being a right-handed pitcher, the advisable streaming options are apparent. Carlos Cortes (8%) is expected to bat near the top of the order in each game, positioning him as the primary recommendation. For leagues with more extensive rosters, Henry Bolte (7%) and Zack Gelof (33%) are worth evaluating.
Royals @ Nationals, vs. Cardinals: The Kansas City Royals’ underperforming offense might find momentum as they play four games across the upcoming four-day period, none of which feature an elite opposing pitcher. With three left-handed pitchers and one right-handed pitcher slated for the mound, Lane Thomas (1%) warrants consideration, particularly since he might occupy the leadoff spot in the three games initiated by southpaws.