Greetings as we reach the midpoint of the 2025 season! Following the Thursday kickoff by the Broncos and Raiders, Sunday brings a comprehensive look at teams heading into the decisive phase. The final nine weeks are shaping up to be unpredictable, with teams closely positioned in the standings.
Consider that in the NFC West, three teams share a six-win record, while the NFC North sees every team with either four or five wins to date. Furthermore, the current projected playoff lineup has teams like the Kansas City Chiefs and Baltimore Ravens on the periphery, while teams like the Buffalo Bills and Detroit Lions are currently in wild card positions. Will this remain consistent through the second half, or will these teams regain their top form? We will begin to see this unfold starting in Week 10.
Before the start of the games — beginning early Sunday with the international match in Berlin, Germany — let’s ensure you’re ready with your betting insights. Below are five leading picks for Week 10, along with projections for all other games.
Teams with a bye in Week 10: Dallas, Cincinnati, Tennessee and Kansas City.
NFL odds provided by FanDuel Sportsbook. Place NFL bets at FanDuel and receive $150 in bonus bets with a successful $5 wager.
The Patriots are surging, entering Week 10 riding a six-game winning streak. While there are suggestions that this could be where their streak ends, I disagree. I believe the Buccaneers are too hampered by injuries on offense and are a poor matchup against New England’s defensive setup.
Running back Bucky Irving is again sidelined, meaning Tampa Bay is without their primary rusher against the league’s top-ranked run defense. Additionally, Baker Mayfield’s receiving options are limited. Mike Evans will be out due to ongoing injury issues, and Chris Godwin is also unavailable. This elevates Emeka Egbuka to the primary target. The rookie had a strong start, but his production has been just 117 receiving yards over the past three games, and now he could be closely guarded by Christian Gonzalez.
This situation suggests that the Bucs’ offense will likely struggle, paving the way for New England to secure another narrow victory and improve to 5-0 on the road in 2025.
Projected score: Patriots 27, Buccaneers 20
The pick: Patriots +2.5
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This analysis isn’t simply a reaction to the Packers’ recent home defeat by the Panthers. I believe Green Bay was already focused on this upcoming game — and with good reason. This is a significant confrontation with potential implications for the NFC’s top seed. Ultimately, I see this as a challenging situation for Green Bay for a couple of key reasons.
Firstly, Philadelphia will be well-prepared after their Week 9 bye and has historically performed strongly in such situations, maintaining a 4-0 record after a bye week under Nick Sirianni. The second factor influencing my skepticism about Green Bay on Monday night is the absence of Tucker Kraft, who sustained a season-ending knee injury the previous week. He has been a vital player in their offense, leading the team in receiving yards. Given their relatively inexperienced receiving corps, it might take some time for the offense to re-establish its rhythm, and the Eagles, with their improved defense post-deadline, are unlikely to provide many opportunities for them to do so.
Also, consider this angle: it was the Packers who originally suggested prohibiting the “tush push” maneuver last offseason. Although the vote failed, they initiated the effort to remove it from the game. You can be sure Sirianni will use this as additional motivation in their direct confrontation.
Projected score: Eagles 23, Packers 21
The pick: Eagles +1.5
There is some minor concern that the Bills might experience a dip in performance following their victory over the Chiefs last week. However, I would be more concerned if they weren’t trailing New England in the division standings. They understand they cannot afford further losses, and the Dolphins are not well-positioned to offer significant resistance.
Miami suffered a considerable defeat at home against the Ravens last Thursday, leading to the departure of their general manager, Chris Grier. It also appears that the tenures of both Mike McDaniel and Tua Tagovailoa may be nearing their end. Meanwhile, Josh Allen — who is currently achieving career-best statistics in completion rate (70%) and yards per attempt (8.2) — has generally dominated against the Dolphins. The Bills quarterback holds a 14-2 record and averages three total touchdowns per game against this divisional opponent.
I anticipate Buffalo will establish a significant lead, and Miami will struggle to recover.
Projected score: Bills 33, Dolphins 20
The pick: Bills -9.5
The Cardinals will be relying on Jacoby Brissett for this game. While Arizona’s offense has appeared more effective with Brissett as quarterback compared to Kyler Murray earlier in 2025, I’m not convinced he can match pace with a Seattle team that seems like a formidable contender in the NFC.
Defensively, Seattle should be able to pressure Brissett effectively, considering the Seahawks enter Week 10 with the third-highest number of sacks in the NFL (27). They are also tied for the third-fewest yards allowed per play (4.7) and are ranked fifth in points allowed per game (18.8). Combined with an offense that is among the top five in scoring and tied for the lead in yards per play, Seattle appears to be overwhelmingly strong, particularly when playing at home.
Projected score: Seahawks 27, Cardinals 17
The pick: Seahawks -6.5
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Following C.J. Stroud’s inability to play due to a concussion, the Texans will rely on Davis Mills in Week 10. Although Stroud’s absence undoubtedly lowers Houston’s potential, I still favor the Texans in this situation. Mills is a competent backup, and this game is more about being skeptical of Jacksonville’s performance.
The Jaguars’ offense is proving difficult to trust, especially given Trevor Lawrence’s struggles. He is ranked 32nd among 33 qualified quarterbacks in completion rate this season (59.7%), and the addition of Jakobi Meyers does not automatically resolve these issues. This matchup is even more challenging for Jacksonville considering Lawrence is facing what is arguably the NFL’s best defense without their leading receiver, Brian Thomas Jr., who is out with an ankle injury.
Houston currently leads the league in points allowed per game (15.1) and yards allowed per game (267.4). I anticipate that the Texans will disrupt Jacksonville’s offensive plays sufficiently, so Mills will not need to carry the team to maintain Houston’s control.
Projected score: Texans 23, Jaguars 20
The pick: Texans +1.5
Remaining Games
Falcons at Colts (in Berlin)
Projected score: Colts 30, Falcons 20
The pick: Colts -6.5
Giants at Bears
Projected score: Bears 27, Giants 21
The pick: Bears -4.5
Ravens at Vikings
Projected score: Ravens 24, Vikings 21
The pick: Vikings +4.5
Browns at Jets
Projected score: Browns 23, Jets 20
The pick: Browns -2.5
Saints at Panthers
Projected score: Panthers 24, Saints 20
The pick: Saints +5.5
Rams at 49ers
Projected score: Rams 27, 49ers 24
The pick: 49ers +4.5
Lions at Commanders
Projected score: Lions 33, Commanders 20
The pick: Lions -7.5
Steelers at Chargers
Projected score: Chargers 27, Steelers 23
The pick: Chargers -2.5